Expandable, Functional Hepatocytes Derived from Primary Cells Enable Liver Therapeutics
Sunil K. Mallanna, Soujanya S. Karanth, Joseph E. Marturano, Abhijith Kundadka Kudva, Marcus Lehmann, Julie K. Morse, Morgan Jamiel, Timothy J. Norman, Christopher Wilson, Fabiola Munarin, David J. Broderick, Maxwell Van Buskirk, Esha A. Uddin, Michael Ret, Christopher Steele, , Arnav Chhabra
This study develops a scalable method to expand primary human hepatocytes while preserving their function, enabling improved liver cell therapy.
bioRxiv · Dec 28, 2024 · PreprintBioengineering