Estrogen receptor alpha (ERα) driven trans-regulation of mitotic checkpoint complex (MCC) components affects the clinical outcome of breast cancer
Suryendu Saha, Debanil Dhar, Stuti Roy, Ratnadip Paul, Anindya Mukhopadhyay, Arnab Gupta, Somsubhra Nath
This study investigates how ERα regulates MCC components in breast cancer, showing that ERα promotes transcription of MAD2 and BUB1B, affecting mitotic outcomes and patient survival.
bioRxiv · Aug 31, 2024 · PreprintCancer Biology