Author

Samuel Tremblay‐Belzile

Memorial Sloan Kettering Cancer CenterORCID 0000-0002-9993-6700Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Agnel J. SfeiriD· 1 shared Alain VerreaultiD· 1 shared Audrey Loubert‐Hudon· 1 shared Danielle VargasiD· 1 shared James G. OmichinskiiD· 1 shared Juliana Andrea Pérez Di GiorgioiD· 1 shared Marco TiganoiD· 1 shared Normand Brisson· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 16 mutual co-author links

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1 shared paperMolecular Biology

Agnel J. SfeirORCID

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2 papers

Recent·Most cited

Nuclear sensing of mitochondrial DNA breaks enhances immune surveillance

Marco Tigano, Danielle Vargas, Samuel Tremblay‐Belzile, Yi Fu, Agnel J. Sfeir

The paper shows that mitochondrial DNA breaks trigger a type I interferon response through nuclear sensing, enhancing immune surveillance against genotoxic stress.

Nature · Feb 24, 2021Peer-reviewedMolecular Biology

Short-range, orientation-reversing template-switching events occur at a high frequency in the human and yeast genomes

Samuel Tremblay‐Belzile, Juliana Andrea Pérez Di Giorgio, Audrey Loubert‐Hudon, Alain Verreault, Normand Brisson, James G. Omichinski

The paper develops SCARR to identify DNA rearrangements and finds high-frequency short-range orientation-reversing events in human and yeast genomes, likely via template-switching during replication.

bioRxiv · Mar 6, 2020 · PreprintGenomics