Ali Hadizadeh Esfahani

This paper identifies methodological challenges in translational drug response modeling in cancer and highlights the need for more robust and transferable modeling approaches.

The paper identifies metastable regimes in biochemical networks and links parameter sensitivity to cancer-specific alterations using tropical geometry and signaling network analysis.

The paper systematically analyzes chaperome deregulation across 22 solid cancers using gene expression data and develops a tool to visualize proteostasis alterations.