Author

Neal D. Freedman

Division of Cancer Epidemiology and GeneticsORCID 0000-0003-0074-1098Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 4

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 4 Research Focus:GWAS / association mapping· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:GWAS summary statistics· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Mitchell J. MachielaiD· 4 shared Stephen Jacob ChanockiD· 4 shared Wen‐Yi HuangiD· 4 shared Christopher A. HaimaniD· 3 shared David V. ContiiD· 3 shared Hans G. LiljaiD· 3 shared John P. ShelleyiD· 3 shared John S. WitteiD· 3 shared

Activity by Year

2023-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersGenetic & Genomic Medicine

Mitchell J. MachielaORCID

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4 papers

Recent·Most cited

Genetic & Genomic MedicineHuman Genetics and Genomics AdvancesPeer-reviewedJun 6, 2024

Transcriptome-Wide Association Analysis Identifies Novel Candidate Susceptibility Genes for Prostate-Specific Antigen Levels in Men Without Prostate Cancer

Dorothy M. Chen, Ruocheng Dong, Linda Kachuri…·Rebecca E. Graff

4 citations

humanbulk RNA-seq

𝕏 PostBluesky

Genetic & Genomic MedicinemedRxivPreprintOct 27, 2023

Genome-wide association study of prostate-specific antigen levels in 392,522 men identifies new loci and improves cross-ancestry prediction

Thomas J. Hoffmann, Rebecca E. Graff, Ravi Madduri…·John S. Witte

This study identifies 447 new genetic variants associated with prostate-specific antigen levels across multiple ancestries and shows improved cross-ancestry prediction of PSA, with implications for personalized prostate cancer screening.

3 citations

humanGWAS summary statistics

𝕏 PostBluesky

Genetic & Genomic MedicineNature MedicinePeer-reviewedJun 1, 2023

Genetically Adjusted PSA Levels for Prostate Cancer Screening

Linda Kachuri, Thomas J. Hoffmann, Yu Jiang…·John S. Witte

This study develops a polygenic score to adjust PSA levels, improving the detection of aggressive prostate cancer while reducing unnecessary biopsies.

80 citationstop 4%

humanbulk RNA-seq

𝕏 PostBluesky

Genetic & Genomic MedicinemedRxivPreprintJan 28, 2023

Population analyses of mosaic X chromosome loss identify genetic drivers and widespread signatures of cellular selection

Aoxing Liu, Giulio Genovese, Yajie Zhao…·Mitchell J. Machiela

This study identifies genetic drivers and cellular selection signatures of mosaic X chromosome loss in women using large-scale population data and polygenic scores.

7 citations

humanwhole-genome sequencing

𝕏 PostBluesky