The Helicobacter pylori orphan ATTAAT-specific methyltransferase M.Hpy99XIX plays a central role in the coordinated regulation of genes involved in iron metabolism
Wilhelm Gottschall, Florent Ailloud, Christine Josenhans, Sebastian Suerbaum
This paper identifies M.Hpy99XIX as an orphan methyltransferase in H. pylori that regulates iron metabolism genes through promoter methylation, affecting metal ion susceptibility and oxidative stress.
mBio · Jun 9, 2025Peer-reviewedMicrobiology