Author

Laura Rueda-Gensini

Division of Computational Genomics and Systems Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany;ORCID 0000-0003-0138-7393Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:deep learning· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:scRNA-seq· 2 Assay:ATAC-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:CRISPR screen· 1

Frequent Co-Authors

Moritz MalliD· 2 shared Oliver StegleiD· 2 shared Alexandra Pettet· 1 shared Ana Munoz-Verdu· 1 shared Benjamin MederiD· 1 shared Bettina WeigeliD· 1 shared Brian ClarkeiD· 1 shared Bryce LimiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersGenomics

Moritz MallORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintNov 10, 2026

Time-resolved single-cell screening reveals the dynamic regulatory architecture of human cardiogenesis

Dominik Lindenhofer, Katharina Mikulik, Stefanie Mantz…·Lars Michael Steinmetz

This study uses time-resolved single-cell CRISPR screening and a multiome atlas to uncover dynamic gene regulatory networks in human cardiogenesis, identifying stage-specific regulators and CHD-linked gene functions.

DOI 10.64898/2026.11.03.764059

humanscRNA-seq

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Cancer BiologybioRxivPreprintMay 13, 2025

Decoding Plasticity Regulators and Transition Trajectories in Glioblastoma with Single-cell Multiomics

Manu Saraswat, Laura Rueda-Gensini, Elisa Heinzelmann…·Moritz Mall

This study uses single-cell multiomics to identify regulatory programs and plasticity regulators in glioblastoma, revealing MYT1L as a key repressor of malignant plasticity.

10 citations

humanscRNA-seq

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