Author

Bryce Lim

German Cancer Research CenterORCID 0000-0002-5688-3952Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:ATAC-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Moritz MalliD· 3 shared Aryan KamaliD· 1 shared Aubry K. MilleriD· 1 shared Bettina WeigeliD· 1 shared Borja Gomez RamosiD· 1 shared Cedar SchlooiD· 1 shared Daniel N. KazdaliD· 1 shared Daniel Pastor‐FloresiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersCancer Biology

Moritz MallORCID

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3 papers

Recent·Most cited

Cancer BiologyNature CommunicationsPeer-reviewedApr 11, 2026

Differential KEAP1/NRF2 mediated signaling widens the therapeutic window of redox-targeting drugs in SCLC therapy

Jana Samarin, Hana Nůsková, Piotr Fabrowski…·Nikolas Gunkel

The paper shows that activating the NRF2 pathway can safely increase the dose of TXNRD1 inhibitors in SCLC treatment without harming healthy tissues.

4 citationstop 3%

humanexperimental assay

Cancer BiologybioRxivPreprintMay 13, 2025

Decoding Plasticity Regulators and Transition Trajectories in Glioblastoma with Single-cell Multiomics

Manu Saraswat, Laura Rueda-Gensini, Elisa Heinzelmann…·Moritz Mall

This study uses single-cell multiomics to identify regulatory programs and plasticity regulators in glioblastoma, revealing MYT1L as a key repressor of malignant plasticity.

10 citations

Cancer BiologyNature GeneticsPeer-reviewedFeb 13, 2025

Active repression of cell fate plasticity by PROX1 safeguards hepatocyte identity and prevents liver tumourigenesis

Bryce Lim, Aryan Kamal, Borja Gomez Ramos…·Moritz Mall

The paper identifies PROX1 as a safeguard repressor that maintains hepatocyte identity and prevents liver tumourigenesis by repressing alternate fate regulators.

19 citationstop 2%

mousestatistical model