Author

Andrew A. Peden

University of SheffieldORCID 0000-0003-0144-7712Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Calum HarveyiD· 1 shared Catherine C.Y. ChangiD· 1 shared Cleide Dos Santos SouzaiD· 1 shared David Ezra GordoniD· 1 shared Elaina Marie MeltoniD· 1 shared Emily J GravesiD· 1 shared Guillaume M. HautbergueiD· 1 shared Jack N.G. MarshalliD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenetics

Calum HarveyORCID

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2 papers

Recent·Most cited

GeneticsLife Science AlliancePeer-reviewedOct 14, 2022

Low expression of EXOSC2 protects against clinical COVID-19 and impedes SARS-CoV-2 replication

Tobias Moll, Valerie Odon, Calum Harvey…·Johnathan Cooper‐Knock

The paper identifies reduced EXOSC2 expression as protective against SARS-CoV-2 infection and clinical COVID-19 by inhibiting viral replication and upregulating antiviral genes.

4 citations

humanbulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintAug 7, 2020

Acat1 gene KO restores TGN cholesterol deficiency in mutant NPC1 cells and expands mutant Npc1 mouse lifespan

Maximillian A. Rogers, Catherine C.Y. Chang, Robert A. Maue…·Ta‐Yuan Chang

The paper shows that Acat1 gene knockout improves cholesterol levels and extends lifespan in mutant Npc1 mice by correcting cholesterol mislocalization.

1 citation

mouseexperimental assay

𝕏 PostBluesky