Patrick G. S. Grady

This study uses paleogenomes of dire wolves to resolve their evolutionary relationships and identify genes under diversifying selection.

This study investigates genetic factors contributing to high cancer susceptibility in marsupials by comparing genome expansions of oncogenes between dasyurid and non-dasyurid species.

The paper produces gapless assemblies of ape sex chromosomes for five great apes and a lesser ape, revealing divergence in Y chromosomes and evolutionary dynamics.

The paper presents methylation profiles for two maple species using long-read sequencing to quantify methylation across all 5mC contexts, revealing patterns in transposable elements and gene regulation.

The paper presents the complete sequence of a human Y chromosome, correcting errors in the GRCh38 reference and adding over 30 million base pairs.

A gapless 3.055 billion bp human genome from HiFi and ultra-long nanopore reads resolves all centromeric arrays and acrocentric p-arms, adding 182 Mbp of new sequence.

The paper presents the first de novo repeat discovery and annotation of a complete human reference genome, identifying novel satellite arrays and characterizing new classes of complex repeats.

This paper introduces a low-cost, streamlined amplicon-based method for SARS-CoV-2 sequencing that is comparable to existing methods in accuracy and scalability.