Author

John Campbell Chambers

Imperial College Healthcare NHS TrustORCID 0000-0003-0209-4541Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 16 Genetic & Genomic Medicine· 7 Genetics· 5 Bioinformatics· 2 Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 32 Approach:statistical model· 26 Research Focus:variant effect prediction· 11 Research Focus:GWAS / association mapping· 10 Assay:whole-exome sequencing· 10 Research Focus:differential expression· 9 Assay:whole-genome sequencing· 8 Research Focus:database / resource· 6

Frequent Co-Authors

Donald W. BowdeniD· 15 shared Michael BoehnkeiD· 15 shared Adolfo CorreaiD· 12 shared Gil AtzmoniD· 12 shared Lori L. BonnycastleiD· 12 shared Ravindranath DuggiralaiD· 12 shared Tõnu EskoiD· 12 shared Daniel I. ChasmaniD· 11 shared

Activity by Year

2017-2026 · peak 8/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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15 shared papersGenomics

Donald W. BowdenORCID

Mutual co-authors in cluster

Author profile →

33 papers

Recent·Most cited

GenomicsbioRxivPreprintJan 31, 2019

Disease and phenotype relevant genetic variants identified from histone acetylomes in human hearts

Wilson Lek Wen Tan, Chukwuemeka George Anene-Nzelu, Eleanor Wong…·Roger Foo

The paper identifies genetic variants associated with heart failure by analyzing histone acetylation QTLs in human heart tissue.

1 citation

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GeneticsbioRxivPreprintJul 31, 2018

Genetic discovery and translational decision support from exome sequencing of 20,791 type 2 diabetes cases and 24,440 controls from five ancestries

Jason A. Flannick, Josep Maria Mercader, Christian Fuchsberger…·Markku Laakso

This study identifies rare genetic variants associated with type 2 diabetes using exome sequencing of 20,791 cases and 24,440 controls, and provides a Bayesian framework to improve variant prioritization.

3 citations

humanwhole-exome sequencing

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GenomicsHypertensionPeer-reviewedJul 24, 2017

Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney

Louise V. Wain, Ahmad Vaez, Rick Jansen…·Tamara B. Harris

This study identifies 6 new blood pressure loci and 48 genes involved in BP regulation using GWAS and gene expression data from blood and kidney tissues.

162 citationstop 1%

humanGWAS summary statistics

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