Author

Siyuan Chen

Pennsylvania State UniversityORCID 0000-0003-0219-3558Unclaimed ORCID profile · follow to get notified of new preprints

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Siyuan Chen1 paper · Fred Hutch Cancer Center

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Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Approach:statistical model· 1

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Ani W ManichaikuliD· 1 shared Chen WangiD· 1 shared Dajiang J. LiuiD· 1 shared Jerome I. RotteriD· 1 shared Kent D. TayloriD· 1 shared Stephen S. RichiD· 1 shared Xiuqing GuoiD· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperGenetics

Ani W ManichaikulORCID

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1 paper

Recent·Most cited

GeneticsbioRxivPreprintApr 17, 2025

Trans-ancestry Mendelian Randomization Discovers Novel Causal Genes for Autoimmune Disease Traits

Siyuan Chen, Chen Wang, Kent D. Taylor…·Dajiang J. Liu

This paper develops a method to improve Mendelian randomization analysis by integrating GWAS results across ancestries, enhancing accuracy and power in discovering causal genes for autoimmune diseases.

DOI 10.1101/2025.04.17.649410

GWAS summary statisticsstatistical model

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