Fabrizio Cleri

This study shows that UDG recognizes DNA damage in the nucleosome through strict structural conditions and potential mechanical deformation of DNA.

This study uses molecular dynamics simulations to show that DNA mechanics can induce base-flipping, facilitating UDG recognition of uracil bases in chromatin.

This study uses molecular dynamics simulations to investigate how PARP-1's Zn1 and Zn2 domains interact with DNA single-strand breaks, revealing their cooperative role in SSB recognition.