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Parvathy A. P. Sarma

Centre National de la Recherche ScientifiqueORCID 0009-0004-4684-1910Unclaimed ORCID profile · follow to get notified of new preprints

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Corinne AbbadieiD· 1 shared Fabrizio CleriiD· 1 shared

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1 shared paperMolecular Biology

Corinne AbbadieORCID

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Molecular BiologyScientific ReportsPeer-reviewedOct 6, 2024

Cooperative dynamics of PARP-1 Zinc-finger domains in the detection of DNA single-strand breaks

Parvathy A. P. Sarma, Corinne Abbadie, Fabrizio Cleri

This study uses molecular dynamics simulations to investigate how PARP-1's Zn1 and Zn2 domains interact with DNA single-strand breaks, revealing their cooperative role in SSB recognition.

14 citations

statistical model

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