Author
St. Jude Children's Research HospitalORCID 0000-0003-0303-5658Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Anna Eames Seffernick, Xueyuan Cao, Cheng Cheng…·Stanley B Pounds
BEAM integrates multiple omics profiles with multiple clinical outcomes using bootstrap resampling to identify significant associations, outperforming existing methods in simulations and a pediatric leukemia application.
Kashi Raj Bhattarai, Robert J. Mobley, Kelly R. Barnett…·Daniel Savic
The paper identifies noncoding genetic variants affecting chemotherapy response in childhood ALL by linking them to gene regulatory elements and showing functional impacts on drug sensitivity.
Kelly R. Barnett, Robert J. Mobley, Jonathan D. Diedrich…·Daniel Savic
The paper maps chromatin accessibility in B-ALL subtypes using ATAC-seq, identifies TFs and genetic variants influencing chromatin architecture and gene regulation.
Chuang Jiang, Wenjian Yang, Takaya Moriyama…·Jun J.J. Yang
This study identifies NT5C2 germline variants affecting 6-MP metabolism in ALL patients, showing two independent variants influence TGN levels.