Author

Ángel Alexander Cabrera

ORCID 0000-0003-0348-3362Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Approach:machine learning (classical)· 2 Approach:benchmark study· 1 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Alex Beatson· 2 shared Anne Elizabeth CarpenteriD· 2 shared Daniil A. BoikoiD· 2 shared Katherine TittertoniD· 2 shared Shantanu SinghiD· 2 shared Srijit SealiD· 2 shared Adit Shah· 1 shared Alex BäuerleiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersPharmacology & Toxicology

Alex Beatson

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Pharmacology & ToxicologyCell SystemsPeer-reviewedMar 27, 2026

✦ In-depth digest

Cell Painting for cytotoxicity and mode-of-action analysis in primary human hepatocytes

Jessica Ewald, Katherine Titterton, Alex Bäuerle…·Shantanu Singh

Cell Painting in primary human hepatocytes exposed to 1,085 compounds detects bioactivity at lower concentrations than cytotoxicity assays and predicts cell-based, but not cell-free, ToxCast endpoints across feature extractors.

16 citationstop 1%

humanimaging

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BioinformaticsbioRxivPreprintApr 27, 2025

Small molecule bioactivity benchmarks are often well-predicted by counting cells

Srijit Seal, William Dee, Adit Shah…·Anne Elizabeth Carpenter

The paper shows that cell counting can predict compound bioactivity as well as Cell Painting or gene expression, but Cell Painting adds unique value in protein-target-specific benchmarks.

4 citations

proteomicsbulk RNA-seq

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