Inferring immunological control mechanisms from TKI dose alterations in CML patients
Tom Hähnel, Christoph Baldow, Artur C. Fassoni, Joëlle Guilhot, François Guilhot, Susanne Saußele, Satu M. Mustjoki, Stefanie Jilg, Philipp Jakob Jost, Stéphanie Dulucq, François‐Xavier Mahon, Ingo Roeder, Ingmar Glauche
The paper uses a mathematical model to classify CML patients based on immune response dynamics following TKI dose alterations, identifying different mechanisms for achieving treatment-free remission.
bioRxiv · Aug 1, 2019 · PreprintSystems Biology