BioinformaticsbioRxivPreprint
Global statistical models of protein coevolution reveal higher-order sectors beyond those obtained from structure alone
Carina Shiau, Haobo Wang, Young Lee, Sergey Ovchinnikov
The paper introduces a spectral clustering model to identify protein sectors from sequence coevolution data, revealing networks of residues not captured by structural contacts.
DOI 10.1101/2022.05.27.493723