Carla Perpiñá-Clérigues

This study identifies sex-specific miRNA profiles in urinary extracellular vesicles of alcohol use disorder patients, revealing potential biomarkers and mechanistic insights into sex differences in AUD.

MetaOmixTools provides a web-based platform for meta-analysis of ranked features and functional enrichment, enabling integration of multi-study omics data to identify conserved biological insights.

This study characterizes the lipidomic profile of urine extracellular vesicles in male alcohol use disorder patients, identifying FA 22:0 as a potential biomarker linked to inflammation and metabolic dysfunction.

This study integrates miRNomic and lipidomic analysis of plasma extracellular vesicles from AUD patients and controls to identify sex-based molecular signatures and their functional implications.

This study investigates the effects of MSC-EVs on neuroinflammation and behavioral impairments caused by chronic alcohol consumption in mice, finding that MSC-EVs reduce inflammation and improve cognitive and addictive-like behaviors.

This study investigates how TLR4 and sex affect lipidome changes in EVs from chronically alcohol-exposed mice, identifying lipid subclasses linked to inflammation and EV biogenesis.

This study shows that mesenchymal stem cell-derived extracellular vesicles reduce hippocampal NLRP3 inflammasome activation and inflammation in adolescent mice after binge ethanol treatment.