Systems BiologyPLoS Computational BiologyPeer-reviewed
Determining clinically relevant features in cytometry data using persistent homology
Soham Mukherjee, Darren Wethington, Tamal K. Dey, Jayajit Das
This paper applies persistent homology to cytometry data to identify structural differences between healthy donors and COVID-19 patients, revealing downregulation of T-bet and Eomes in patient non-naive CD8+ T cells.