Pavlína Pokorná

This study reveals a loaded-spring mechanism by which U2 snRNP recognizes the branch site through spontaneous strand invasion driven by conformational energy release.

This study uses molecular dynamics simulations to explore the folding pathways of an RNA G-quadruplex, revealing multi-pathway mechanisms and highlighting challenges in simulating non-canonical RNA structures.

This study uses molecular dynamics simulations to explore the folding pathways of a parallel G-quadruplex DNA structure, revealing multiple folding paths and limitations of current force fields.

The paper uses molecular dynamics simulations to study RNA-FUS interactions, revealing conformational heterogeneity and dynamic behavior that complement experimental data.

This study uses atomistic simulations to observe spontaneous RNA binding to RRM domains of HuR and SRSF1 proteins, revealing dynamic binding pathways and the need for modified force fields.