Sébastien Campagne

The paper investigates how variants in OCA2 exon 10 affect splicing and pigmentation, showing that some variants increase exon skipping and contribute to hypopigmentation.

This study identifies common pharmacophores in splicing modifiers targeting A-1 bulged 5'-splice sites using structural and computational methods.

The paper uses molecular dynamics simulations to study RNA-FUS interactions, revealing conformational heterogeneity and dynamic behavior that complement experimental data.

This study identifies RBM39's role in autoregulating its own pre-mRNA splicing through interactions with U1 and U2 snRNPs, offering insights for alternative cancer therapies.