Tao Wang

The paper identifies chromatin regulatory genes as genetic modifiers of conotruncal heart defects in 22q11.2 deletion syndrome and links them to sporadic congenital heart disease.

The paper estimates heritability for height and BMI using whole-genome sequence data and finds that rare variants contribute significantly to the missing heritability.

SCCNV identifies copy number variations from single-cell whole-genome sequencing data by adjusting for amplification bias.

This study uses TOPMed whole genome sequences to improve imputation quality and detect rare variant associations in admixed African and Hispanic/Latino populations, identifying two novel associations with hematological traits.

This study uses single-cell whole-genome sequencing to analyze somatic mutations in B lymphocytes across the human lifespan, finding age-related mutation accumulation and potential cancer-related events.