The paper describes a minimally invasive method for delivering AAV vectors to pig livers but finds low vector retention and no detectable editing in vivo.

2 citations

plant (other)experimental assay

𝕏 PostBluesky

GenomicsGeneticsPeer-reviewedDec 18, 2020

Infertility due to defective sperm flagella caused by an intronic deletion in DNAH17 that perturbs splicing

Adéla Nosková, Maya Hiltpold, Fredi Janett…·Hubert Pausch

The paper identifies an intronic deletion in DNAH17 causing infertility in pigs due to defective sperm flagella by disrupting splicing and axoneme assembly.

14 citations

plant (other)statistical model

𝕏 PostBluesky

Molecular BiologybioRxivPreprintNov 17, 2020

Development of a mass-spectrometry based method for the identification of the in vivo whole blood and plasma ADP-ribosylomes

Stephanie C. Lüthi, Anna Howald, Kathrin Nowak…·Michael O. Hottiger

The paper develops a mass-spectrometry method to identify ADP-ribosylomes in whole blood and plasma, finding 60 ADP-ribosylated proteins in LPS-treated pigs.

DOI 10.1101/2020.11.17.384719

plant (other)proteomics

𝕏 PostBluesky