Author

Ernesto Alejandro Segredo-Otero

New York UniversityORCID 0000-0003-0680-5961Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1 Organism:virus· 1

Frequent Co-Authors

David GreshamiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

1 paper

Recent·Most cited

Evolutionary BiologybioRxivPreprintJul 18, 2025

Intracellular replication dynamics of influenza A virus impose strong bottleneck effects

Ernesto Alejandro Segredo-Otero, David Gresham

This study uses stochastic modeling to show that intracellular replication of influenza A virus creates strong bottleneck effects, reducing genetic diversity and increasing genetic drift.

DOI 10.1101/2025.07.18.665558

virusstatistical model

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