Investigating the Role of Different Co-receptors on T-cell Activation Through IFN-γ Secretion Using Spatially Controlled Cell Monitoring Platform
Naiara Lartitegui-Meneses, Enrique Azuaje‐Hualde, Andrea Merino…·Lourdes Basabe‐Desmonts
This paper adapts the CellStudio platform to study T-cell activation by co-receptor engagement, showing that combined anti-CD3 and anti-CD4 stimulation leads to stronger IFN-γ secretion and altered contact morphology in Jurkat T-cells.