Adai Colom

This paper adapts the CellStudio platform to study T-cell activation by co-receptor engagement, showing that combined anti-CD3 and anti-CD4 stimulation leads to stronger IFN-γ secretion and altered contact morphology in Jurkat T-cells.

This study shows HRS forms 2D condensates that drive flat clathrin lattice assembly on endosomes, with cholesterol enhancing this process.

This study identifies an ancient membrane fission mechanism in Asgard archaea, showing ESCRT-III's role in cell compartmentalization predates eukaryogenesis.

The paper demonstrates that adherent cells maintain spatial gradients of membrane tension through actin dynamics and membrane-cortex attachments, with tension lowest at adhesion edges and highest at protrusions.