Chandra Shekhar Verma

This study uses multiscale simulations to reveal how SDS disrupts MS2 bacteriophage capsid, showing pH-dependent effects and molecular mechanisms of surfactant-virus interaction.

This paper identifies evolutionarily conserved LRR proteins in velvet worm slime that form receptor-like structures, enabling reversible supramolecular network formation in bioadhesive fibers.

This paper designs histidine-rich peptides with cation-π interactions to create stable coacervates for controlled intracellular delivery of macromolecules, including CRISPR/Cas9, into cells.

This study shows RA signaling promotes luminal identity in prostate progenitors through Foxa1, and identifies a loss-of-function mutation in Foxa1 linked to prostate cancer dedifferentiation.

This study manipulates phase-separating peptide sequences to control coacervate microdroplet properties and intracellular delivery kinetics of macromolecules.

The paper investigates how surface charge mutations affect PETase activity on different PET substrates and identifies an engineered variant with improved degradation efficiency.

Structome provides a web server to identify structural neighbors of proteins and generate datasets for structure-based phylogenetics using precomputed data.

The paper identifies charge-absent regions in proteins involved in liquid-liquid phase separation and suggests their role in condensate formation through hydrophobic interactions.

PhosIDP visualizes how phosphorylation affects charge and fold propensity in intrinsically disordered regions, aiding in functional interpretation of phosphorylation effects.

The paper builds and interprets Random Forest models to predict Cell-Penetrating Peptides (CPPs) using amino acid sequence features, achieving ~96% accuracy and providing insights into key predictive features.