Author

Devesh Sharma

University of California, San FranciscoORCID 0000-0003-0761-6732Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2

Frequent Co-Authors

Eric SoupèneiD· 2 shared M. Kyle CromeriD· 2 shared Matthew Hebden PorteusiD· 2 shared Simon N. ChuiD· 2 shared Travis McCrearyiD· 2 shared Aadit P. ShahiD· 1 shared Beeke WienertiD· 1 shared Benjamin J. LeschiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersSynthetic Biology

Eric SoupèneORCID

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2 papers

Recent·Most cited

Synthetic BiologybioRxivPreprintApr 12, 2024

Engineering inducible signaling receptors to enable erythropoietin-free erythropoiesis

Aadit P. Shah, Kiran R. Majeti, Freja K. Ekman…·M. Kyle Cromer

This paper develops small molecule-inducible EPO receptors to enable erythropoiesis without recombinant EPO, reducing costs and improving scalability of RBC manufacturing.

DOI 10.1101/2024.04.12.589260

humanexperimental assay

Molecular BiologybioRxivPreprintSep 1, 2023

Dual α-globin and truncated erythropoietin receptor knock-in restores hemoglobin production in α-thalassemia major-derived hematopoietic stem and progenitor cells

Simon N. Chu, Eric Soupène, Beeke Wienert…·M. Kyle Cromer

This paper describes a genome editing strategy that restores hemoglobin production in α-thalassemia major-derived hematopoietic stem and progenitor cells by integrating a functional α-globin gene and a truncated erythropoietin receptor.

3 citations

humanexperimental assay