Author
University of California, San FranciscoORCID 0000-0002-2511-3517Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
5 papers
Recent·Most cited
Kun Jia, Eric Soupène, Roshani Sinha…·M. Kyle Cromer
This paper develops a combinatorial base editing strategy to enhance erythroid lineage amplification and disease correction in hematopoietic stem and progenitor cells.
Lay Teng Ang, Sherry Li Zheng, Kevin J. Liu…·Kyle M. Loh
The paper identifies a primed endothelial progenitor that requires VEGF/ERK inhibition to differentiate into vein endothelial cells, revealing a two-step process for vein development.
William N. Feist, Sofia E. Luna, Kaya Ben-Efraim…·Matthew Hebden Porteus
This paper describes engineering hematopoietic stem cells to produce CCR5 knockout cells and secrete HIV-1 inhibiting antibodies, aiming for a one-time cure for HIV-1.
Aadit P. Shah, Kiran R. Majeti, Freja K. Ekman…·M. Kyle Cromer
This paper develops small molecule-inducible EPO receptors to enable erythropoiesis without recombinant EPO, reducing costs and improving scalability of RBC manufacturing.
M. Kyle Cromer, Joab Camarena, Renata M. Martin…·Matthew Hebden Porteus
This study replaces the HBA1 gene with HBB in β-thalassemia-derived HSPCs using CRISPR, normalizing globin ratios and restoring functional hemoglobin.