Author
Y‐h. Taguchi
Chuo UniversityORCID 0000-0003-0867-8986Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2016-2026 · peak 8/yrCo-Author Collaboration Network
10 top collaborators · 6 mutual co-author links45 papers
Recent·Most cited
- BioinformaticsComputers in Biology and MedicinePeer-reviewed
Discriminating the Single-cell Gene Regulatory Networks of Human Pancreatic Islets: A Novel Deep Learning Application
This study develops a deep learning application to classify single-cell gene regulatory networks from pancreatic islets, finding that VGG19 performs best in distinguishing healthy from T2D networks.
- BioinformaticsKnowledge-Based SystemsPeer-reviewed
Mathematical formulation and application of kernel tensor decomposition based unsupervised feature extraction
This paper introduces a kernel-based tensor decomposition method for unsupervised feature extraction and evaluates its performance on synthetic and real data, showing it outperforms or matches traditional tensor decomposition in large p small n scenarios.
- BioinformaticsEuropean Journal of Pharmaceutical SciencesPeer-reviewed
Novel analysis of drug-drug interactions reveals the appearance of non-linear dose dependence under the single drug treatment
This study uses tensor decomposition to analyze gene expression data and finds non-linear dose dependence can occur with single drugs, not just drug combinations.
6 citations - Genetic & Genomic MedicineLecture notes in computer sciencePeer-reviewed
End-to-End Deep Learning for Detecting Metastatic Breast Cancer in Axillary Lymph Node from Digital Pathology Images
Turki Turki, Anmar Al-Sharif, Y‐h. Taguchi
This paper develops and evaluates deep learning models to detect metastatic breast cancer in axillary lymph nodes using digital pathology images, finding DenseNet121 achieves the highest performance.
- BioinformaticsGenesPeer-reviewed
Tensor-decomposition-based unsupervised feature extraction applied to prostate cancer multiomics data
This paper introduces a tensor-decomposition-based unsupervised feature extraction method for multiomics data, showing it outperforms existing methods in selecting biologically relevant genes.
5 citations - BioinformaticsScientific ReportsPeer-reviewed
Identification of miRNA signatures for kidney renal clear cell carcinoma using the tensor-decomposition method
The paper uses tensor decomposition to identify miRNA signatures and associated genes in kidney renal clear cell carcinoma, finding 23 genes correlated with patient survival and demonstrating better performance than traditional methods.
20 citations - BioinformaticsFrontiers in GeneticsPeer-reviewed
Universal nature of drug treatment responses in drug-tissue-wide model-animal experiments using tensordecomposition-based unsupervised featureextraction
The paper applies tensor decomposition-based unsupervised feature extraction to gene expression data from drug-treated mouse tissues, identifying common drug effects across tissue groups.
6 citations - BioinformaticsCurrent Pharmaceutical DesignPeer-reviewed
Neurological disorder drug discovery from gene expression with tensor decomposition
The paper screens genes differentially expressed in Alzheimer's disease model mice and finds overlap with drug-treated human cell lines using tensor decomposition.
- BioinformaticsFrontiers in GeneticsPeer-reviewed
Tensor decomposition-Based Unsupervised Feature Extraction Applied to Single-Cell Gene Expression Analysis
This paper applies tensor decomposition-based unsupervised feature extraction to integrate human and mouse scRNA-seq data, improving gene selection and identifying potential regulatory transcription factors.
- BioinformaticsbioRxivPreprint
Multiomics data analysis using tensor decomposition based unsupervised feature extraction --Comparison with DIABLO--
The paper proposes tensor decomposition for multiomics data integration and compares it to DIABLO, showing successful integration of miRNA, mRNA, and proteome data.
1 citation - BioinformaticsbioRxivPreprint
Tensor decomposition--based unsupervised feature extraction for integrated analysis of TCGA data on microRNA expression and promoter methylation of genes in ovarian cancer
This study uses tensor decomposition to identify miRNAs and genes associated with ovarian cancer by integrating miRNA expression and promoter methylation data from TCGA.
DOI 10.1101/380071 - BioinformaticsbioRxivPreprint
Principal component analysis-based unsupervised feature extraction applied to single-cell gene expression analysis
This study uses PCA-based unsupervised feature extraction to identify biologically relevant genes in scRNA-seq data from mouse and human embryonic brain development, outperforming existing methods.
- BioinformaticsScientific ReportsPeer-reviewed
Identification of Candidate Drugs for Heart Failure using Tensor Decomposition-Based Unsupervised Feature Extraction Applied to Integrated Analysis of Gene Expression between Heart Failure and DrugMatrix Datasets
The paper uses tensor decomposition on integrated gene expression data from heart failure and DrugMatrix datasets to identify drug candidates associated with heart failure.
42 citationstop 3% - BioinformaticsbioRxivPreprint
microRNA-mRNA interaction identification in Wilms tumor using principalcomponent analysis based unsupervised feature extraction
The paper identifies miRNA-mRNA interactions in Wilms tumor using principal component analysis to find significant negative correlations between miRNA and mRNA expression.
DOI 10.1101/059295