Author

Dirk Gründemann

ORCID 0000-0003-0914-0299Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Barak RotblatiD· 1 shared Carsten BerndtiD· 1 shared Christian Ballmeyer· 1 shared Daniel J. PicardiD· 1 shared Dennis Roth· 1 shared Filippo BeleggiaiD· 1 shared Frauke Stölting· 1 shared Gabriel LeprivieriD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Barak RotblatORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintJan 27, 2024

Oncogenic RAS signaling is a tumor cell-intrinsic determinant of ferroptosis suppression via induction of the GCH1/BH4 axis

Jonathan K. M. Lim, Frauke Stölting, Dennis Roth…·Gabriel Leprivier

This study shows oncogenic RAS signaling suppresses ferroptosis by upregulating GCH1 and BH4, making RAS-driven cancers resistant to ferroptosis-inducing agents.

1 citation

humanbulk RNA-seq

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