Author

Alexander Holloway

The University of QueenslandORCID 0000-0003-0917-7235Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Approach:Bayesian inference· 1 Assay:bulk RNA-seq· 1 Research Focus:eQTL / molecular QTL mapping· 1 Research Focus:fine-mapping· 1 Research Focus:genome assembly· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Peter M. VisscheriD· 2 shared Andres MetspaluiD· 1 shared Arshed Ali QuyyumiiD· 1 shared Athanasios KousathanasiD· 1 shared Biao ZengiD· 1 shared Daniel Trejo BañosiD· 1 shared Etienne J. Orliac· 1 shared Gerhard MoseriD· 1 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Peter M. VisscherORCID

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2 papers

Recent·Most cited

Genetic & Genomic MedicineNature CommunicationsPeer-reviewedNov 30, 2021

Probabilistic inference of the genetic architecture underlying functional enrichment of complex traits

Marion Patxot, Daniel Trejo Baños, Athanasios Kousathanas…·Matthew R. Robinson

The paper introduces a Bayesian model, BayesRR-RC, to infer the genetic architecture of complex traits and finds that most genetic variance is attributed to non-proximal regulatory and coding regions.

42 citationstop 4%

humanwhole-genome sequencing

𝕏 PostBluesky

GeneticsG3 Genes Genomes GeneticsPeer-reviewedJun 9, 2017

Constraints on eQTL fine mapping in the presence of multi-site local regulation of gene expression

Biao Zeng, Luke R. Lloyd‐Jones, Alexander Holloway…·Greg C. Gibson

This study shows that multi-site regulation of gene expression leads to biased eQTL fine mapping and highlights the need for joint multi-site analysis to improve accuracy.

27 citations

humanbulk RNA-seq

𝕏 PostBluesky