OFF-Target Effects of Mycophenolic Acid on BK Polyomavirus Replication in Primary Human Renal Proximal Tubular Epithelial Cells
Caroline A. Hillenbrand, Dorssa Akbari Bani, Océane M. Follonier…·Hans Hellmuth Hirsch
This study investigates how mycophenolic acid (MPA) inhibits BK polyomavirus (BKPyV) replication in renal proximal tubular epithelial cells through off-target effects, showing that guanosine can reverse this inhibition.