NeurosciencebioRxivPreprint
White matter microstructural abnormality precedes cortical volumetric decline in Alzheimer's disease: evidence from data-driven disease progression modelling
Christopher S Parker, Philip S.J. Weston, Hui Gary Zhang…·the Alzheimer’s Disease Neuroimaging Initiative
This study uses data-driven modeling to show that white matter microstructural changes precede cortical volume loss in Alzheimer's disease, suggesting earlier detection through microstructural markers.