Author

Gemma Sole Guardia

Radboud University Medical CenterORCID 0000-0003-1154-8904Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Britt MossinkiD· 1 shared Daan M. PannemaniD· 1 shared David M CassimaniD· 1 shared Devin OglesbeeiD· 1 shared Dirk SchubertiD· 1 shared Eline van HugteiD· 1 shared Ester Perales‐ClementeiD· 1 shared Éva MoravaiD· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Britt MossinkORCID

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1 paper

Recent·Most cited

NeuroscienceCell ReportsPeer-reviewedApr 1, 2020

Mitochondrial dysfunction impairs human neuronal development and reduces neuronal network activity and synchronicity

Teun M. Klein Gunnewiek, Eline van Hugte, Monica Frega…·Tamás Kozicz

This study shows that mitochondrial dysfunction in human neurons, caused by high heteroplasmy of the m.3243A>G variant, leads to impaired neural development, reduced synaptic connectivity, and decreased network activity.

90 citationstop 4%

humanbulk RNA-seq

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