Author

Ester Perales‐Clemente

Mayo ClinicORCID 0000-0002-6333-4070Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Devin OglesbeeiD· 2 shared Noemi Vidal‐Folch· 2 shared Timothy J. NelsoniD· 2 shared Britt MossinkiD· 1 shared Daan M. PannemaniD· 1 shared David M CassimaniD· 1 shared Dirk SchubertiD· 1 shared Eline van HugteiD· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Devin OglesbeeORCID

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2 papers

Recent·Most cited

NeuroscienceCell ReportsPeer-reviewedApr 1, 2020

Mitochondrial dysfunction impairs human neuronal development and reduces neuronal network activity and synchronicity

Teun M. Klein Gunnewiek, Eline van Hugte, Monica Frega…·Tamás Kozicz

This study shows that mitochondrial dysfunction in human neurons, caused by high heteroplasmy of the m.3243A>G variant, leads to impaired neural development, reduced synaptic connectivity, and decreased network activity.

90 citationstop 4%

humanbulk RNA-seq

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Molecular BiologybioRxivPreprintMar 22, 2018

Engineering targeted deletions in the mitochondrial genome

Jarryd M. Campbell, Ester Perales‐Clemente, Hirotaka Ata…·Stephen Carl Ekker

This paper introduces a method to engineer precise deletions in the mitochondrial genome using TALE proteins in zebrafish and human cells.

6 citations

zebrafishhuman

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