Author

Fabien Darfeuille

Centre National de la Recherche ScientifiqueORCID 0000-0003-1167-6113Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Research Focus:database / resource· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Nicolas J. TourasseiD· 2 shared Claire LaysiD· 1 shared Isabelle IostiD· 1 shared Marion FaucheriD· 1 shared Sandrine Chabas· 1 shared Sara MasachisiD· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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2 shared papersBioinformatics

Nicolas J. TourasseORCID

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2 papers

Recent·Most cited

BioinformaticsRNAPeer-reviewedSep 16, 2021

T1TAdb: the database of Type I Toxin-Antitoxin systems

Nicolas J. Tourasse, Fabien Darfeuille

T1TAdb is a database of Type I toxin-antitoxin systems that annotates RNA and protein features, providing structural and functional information for ~1,900 loci across 500 bacterial strains.

26 citations

bacteria (other)DNA methylation

𝕏 PostBluesky

Molecular BiologyeLifePeer-reviewedAug 14, 2019

A genetic selection reveals functional metastable structures embedded in a toxin-encoding mRNA

Sara Masachis, Nicolas J. Tourasse, Claire Lays…·Fabien Darfeuille

The paper identifies metastable RNA structures that inhibit toxin translation in a type I TA system in Helicobacter pylori by selecting suppressor mutations.

19 citations

humanexperimental assay

𝕏 PostBluesky