Author

Léa Da Costa Fernandes

Centre National de la Recherche ScientifiqueORCID 0000-0003-1272-3938Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 1

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Research Focus:benchmarking· 1 Approach:optimal transport· 1 Approach:statistical model· 1

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Béatrice CousiniD· 1 shared David BernardiD· 1 shared François PérèsiD· 1 shared Paul MonsarratiD· 1 shared Sylvain Cussat‐BlanciD· 1 shared

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2026-2026 · peak 1/yr

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1 shared paperSystems Biology

Béatrice CousinORCID

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1 paper

Recent·Most cited

Systems BiologyBiosystemsPeer-reviewedJan 2, 2026

Expert-guided multi-objective optimization: an efficient strategy for parameter estimation of biological systems with limited data.

Léa Da Costa Fernandes, David Bernard, François Pérès…·Sylvain Cussat‐Blanc

This paper introduces a hybrid calibration framework that integrates expert knowledge into multi-objective optimization for biological model parameter estimation, showing improved biological relevance and reduced overfitting.

1 citation

statistical modeloptimal transport

𝕏 PostBluesky