Multi-omics data analysis supporting inheritance of acquired traits in humans
The paper tests if environmental factors like exercise induce correlated changes in human sperm epigenome and somatic transcriptome, supporting epigenetic inheritance.
Author
Institute of Genomics and Integrative BiologyORCID 0000-0003-1306-1497Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
The paper tests if environmental factors like exercise induce correlated changes in human sperm epigenome and somatic transcriptome, supporting epigenetic inheritance.
The paper compares transcriptomic data from Drosophila and rodent models of epigenetic inheritance, identifies phenotypic cross-species conservation and directionality shifts, and confirms findings experimentally in flies.
The paper analyzes transcriptomic data to show BCG vaccination induces long-lasting transcriptomic changes that both mimic and oppose viral infections, offering insights into its potential protection against COVID-19.
INDICO, Anil Kumar Giri, Gauri Prasad…·Dwaipayan Bharadwaj
This study identifies novel genetic loci associated with BMI in Indians through GWAS and explores their epigenetic and regulatory mechanisms.
The paper analyzes gene set overlaps across epigenetic inheritance, adaptation, and canalization in Drosophila to suggest cis regulatory variations contribute to evolutionary adaptation and trans variations arise during genetic canalization.
The paper analyzes multi-omics data to show sperm DNA methylome involvement in evolution, disease, and gene-environment interactions across species.