Author

Ryan Hannam

King's College LondonORCID 0000-0003-1313-297XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 1

Frequent Co-Authors

Alessia AnnibaleiD· 1 shared Dianbo LiuiD· 1 shared Luca AlberganteiD· 1 shared Reimer KühniD· 1 shared

Activity by Year

2017-2018 · peak 1/yr

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4 top collaborators · 2 mutual co-author links

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1 shared paperGenetics

Alessia AnnibaleORCID

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2 papers

Recent·Most cited

Systems BiologybioRxivPreprintDec 23, 2018

High gene dosage changes transcriptional regulation of genetic structures and contributes to diversity and heterogeneity

Dianbo Liu, Ryan Hannam, Luca Albergante

The paper shows that high gene dosages alter transcriptional regulation of genetic structures, leading to monoallelic expression and cell population heterogeneity, with implications for synthetic biology.

DOI 10.1101/505446

𝕏 PostBluesky

GeneticsJournal of Physics A Mathematical and TheoreticalPeer-reviewedSep 1, 2017

Cell reprogramming modelled as transitions in a hierarchy of cell cycles

Ryan Hannam, Alessia Annibale, Reimer Kühn

This paper models cell reprogramming as transitions between hierarchically related cell cycle states, identifying two mechanisms that effectively drive reprogramming.

15 citations

statistical model

𝕏 PostBluesky