Molecular BiologybioRxivPreprint
Amyloid fibrils in frontotemporal lobar degeneration with TDP-43 inclusions are composed of TMEM106B, rather than TDP-43
Yi Xiao Jiang, Qin Cao, Michael R. Sawaya…·David S Eisenberg
The paper identifies TMEM106B, not TDP-43, as the protein composing amyloid fibrils in FTLD-TDP using cryo-EM.
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