GeneticsThe American Journal of Human GeneticsPeer-reviewed
Multi-ancestry fine-mapping improves precision to identify causal genes in transcriptome-wide association studies
Zeyun Lu, Shyamalika Gopalan, Yuan Dong…·Nicholas Mancuso
This paper introduces MA-FOCUS, a multi-ancestry fine-mapping framework that improves the identification of causal genes in TWAS by leveraging ancestry-specific LD and eQTL patterns.
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