Shyamalika Gopalan

The paper introduces the use of tree sequences from the forwards simulator SLiM to enable interoperability between forward-in-time and coalescent simulations.

The paper develops an epigenetic age predictor that accounts for DNA sequence variation in African populations, finding that genetic variants can influence epigenetic age and longevity.

The paper examines the fitness consequences of increased homozygosity in the Himba population, finding a significant association between higher FROH and reduced fertility.

This paper introduces MA-FOCUS, a multi-ancestry fine-mapping framework that improves the identification of causal genes in TWAS by leveraging ancestry-specific LD and eQTL patterns.

The paper analyzes genomic data from the Chabu, a hunter-gatherer group in Ethiopia, revealing a population bottleneck and diverse demographic responses to agropastoralism in East Africa.

Genome-wide association study and integrative analyses identify 27 genes in inflammation and coagulation pathways linked to COVID-19 hospitalization risk and symptomology.

This study identifies DNA methylation markers in human bone to predict age accurately, outperforming morphometric markers.

This study sequenced ancient dog genomes from the Neolithic period in Europe, finding continuity with modern dogs and rejecting a population replacement model and dual origins hypothesis for dog domestication.

The paper identifies age-related DNA methylation patterns in African hunter-gatherer populations and shows that genetic variation at meQTLs influences these associations.

This study shows early European farmers descended directly from Neolithic Aegeans, linking Mediterranean and Central European farmers to southwestern Asia.