Xingyu Gao

This paper introduces TFDesign-sdAb, a deep learning framework for designing therapeutic single-domain antibodies with tailored functionalities, achieving high success rates in generating Protein A-binding sdAbs.

IgGM is a generative model for antibody design that produces high-affinity antibodies through tasks like structure prediction and affinity maturation, validated on multiple antigens.

IgGM is a generative model that designs functional antibodies and nanobodies by predicting sequences and structures simultaneously for a given antigen.