Author

Francisca Hofmann-Vega

Essen University HospitalORCID 0000-0003-1502-2467Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Almke BaderiD· 1 shared Anke Daser· 1 shared Bettina BudeusiD· 1 shared Daniela BegandtiD· 1 shared Eva-Maria HanschmanniD· 1 shared Jagoda Agnieszka SzlachetkoiD· 1 shared Kirsten BruderekiD· 1 shared Mathias SchmidtiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Almke BaderORCID

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1 paper

Recent·Most cited

IL-1α drives a tumor-stroma-neutrophil axis through inflammatory fibroblast activation in head and neck cancer

Eva-Maria Hanschmann, Kirsten Bruderek, Francisca Hofmann-Vega, Mathias Schmidt, Bettina Budeus, Wibke Oberlies, Xiang Wei, Mathis Richter, Simon Lemm, Jagoda Agnieszka Szlachetko, Sarah Ryan, Almke Bader, Anke Daser, S Lang, Daniela Begandt, , Sven Brandau

This study identifies IL-1α as a driver of a tumor-stroma-neutrophil axis in HNSCC by inducing inflammatory fibroblast activation, enhancing neutrophil recruitment and infiltration.

bioRxiv · Jan 22, 2026 · PreprintCancer Biology