Daniela Begandt

This study identifies IL-1α as a driver of a tumor-stroma-neutrophil axis in HNSCC by inducing inflammatory fibroblast activation, enhancing neutrophil recruitment and infiltration.

This study shows that VPS18 mutations disrupt neutrophil maturation by impairing vesicle dynamics and autophagy, leading to neutropenia and recurrent infections.

The paper shows SCAMP3 is essential for neutrophil granule formation and function, with Scamp3-deficient neutrophils showing impaired bacterial killing in vitro.

This study identifies NR4A1 as a neutrophil-intrinsic regulator that reduces stroke severity by limiting inflammation and brain damage through pharmacological modulation.