Author

Anthony Hart

Australian Research CouncilORCID 0000-0003-1557-6515Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Lan K. NguyeniD· 2 shared Sung-young ShiniD· 2 shared Karina Islas Rios· 1 shared Taha O OsmaniD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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2 shared papersSystems Biology

Lan K. NguyenORCID

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2 papers

Recent·Most cited

Systems BiologybioRxivPreprintMay 5, 2026

Network topology dictates sequential drug efficacy through bistability-mediated state switching

Taha O Osman, Karina Islas Rios, Anthony Hart…·Lan K. Nguyen

The paper identifies network topology principles that determine sequential drug efficacy through bistability-mediated state switching.

DOI 10.64898/2026.05.01.722163

statistical modeldrug response / drug discovery

𝕏 PostBluesky

Molecular BiologybioRxivPreprintJan 24, 2023

Systematic Analysis of Network-driven Adaptive Resistance to CDK4/6 and Estrogen Receptor Inhibition using Meta-Dynamic Network Modelling

Anthony Hart, Sung‐Young Shin, Lan K. Nguyen

This paper develops a novel MDN modelling technique to study how heterogeneity influences adaptive resistance to CDK4/6 and estrogen receptor inhibitors through protein signalling dynamics.

1 citation

statistical model

𝕏 PostBluesky