Author

Marina Gorostiola González

Leiden UniversityORCID 0000-0003-1568-0881Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Assay:proteomics· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Adriaan P. IJzermaniD· 2 shared Gerard J. P. van WesteniD· 2 shared Brandon J. BongersiD· 1 shared Herman van VlijmeniD· 1 shared Hugo Gutiérrez‐de‐TerániD· 1 shared K. Ye· 1 shared Laura H. HeitmaniD· 1 shared Willem JespersiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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2 shared papersBioinformatics

Adriaan P. IJzermanORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintSep 29, 2024

A patient-centric knowledge graph approach to prioritize mutants for selective anti-cancer targeting

Marina Gorostiola González, Adriaan P. IJzerman, Gerard J. P. van Westen

This paper introduces a knowledge graph to prioritize cancer mutations for targeted therapy by integrating clinical, functional, and structural data.

DOI 10.1101/2024.09.29.615658

humanproteomics

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BioinformaticsScientific ReportsPeer-reviewedDec 13, 2022

Pan-cancer in silico analysis of somatic mutations in G-protein coupled receptors: The effect of evolutionary conservation and natural variance

Brandon J. Bongers, Marina Gorostiola González, X. Wang…·Gerard J. P. van Westen

This study analyzes somatic mutations in GPCRs across cancer patients and healthy individuals, identifying conserved mutation hotspots and prioritizing GPCRs for further cancer research.

18 citations

humanwhole-exome sequencing

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