Michael R. McLaren

The paper introduces virus-like DNA tracers to improve the accuracy and resolution of wastewater-based pathogen monitoring systems by assessing assay performance and signal decay.

The paper examines how taxonomic bias affects differential-abundance analysis in microbiome studies and proposes methods to mitigate its effects.

The paper identifies and corrects systematic bias in metagenomic sequencing by modeling how bias distorts measurements and validating it across different protocols and datasets.